The Cotney Lab is interested in determining how gene regulatory elements, namely enhancers, control gene expression during mammalian development. We aim to understand how new gene regulatory functions evolve, to identify mechanisms of enhancer function over large genomic distances, and globally identify variants of enhancer sequences that are associated with human disease.
UConn’s Justin Cotney, Ph.D. to be Honored for Research Excellence by Society for Craniofacial Genetics & Developmental Biology 2023-09-20
Rachel receives travel award for upcoming FPWR Symposium 2023-09-18
Nagham receives invitation to speak at Neuroscience 2023 2023-09-11
Postdoc Kevin Child receives ASHG Trainee Research Excellence Award 2023-09-11
Read Rachel Gilmore’s preprint on Angelman syndrome and Prader-Willi cell lines 2023-08-30
Rachel receives Biomedical Science Service Award in Leadership 2023-08-23
UConn HealthDept. of Genetics and Genome Sciences
Cell and Genome Sciences Building R1158
400 Farmington Ave.
Farmington, CT, 06030
I’m thrilled to finally share our discovery of a pathway enabling mtDNA release from mitochondria and activation of the innate immune cGAS-STING pathway, an epic collaboration between Shadelab and @manorlaboratory! Read on for details!
New preprint from the lab! Led by Irfan Kathiriya, we discovered that a sublineage of cardiac precursors is a compartment boundary required for interventricular septation, regulated by TBX5, which controls its integrity, and Slit2 and Netrin1 signaling 1/x
Please join us in Barcelona for the Craniofacial GRS/GRC. We have an exciting lineup of speakers. Meeting is already 55% full and abstract deadline for short talk consideration is March 7. https://www.grc.org/craniofacial-morphogenesis-and-tissue-regeneration-conference/2024/